Hupfel graduated Magna Cum Laude with a B.A. degree from Brown University and earned an M.F.A. from the University of Delaware in 1993. Hupfel taught at the Kansas City Art Institute and at the University of Georgia in Athens, GA. From 1989 to 2002, her work was shown in over 30 exhibitions in galleries and alternative spaces from New York to Atlanta. Hupfel’s photographs are in collections at the Delaware Art Museum, Wilmington, DE; the High Museum of Art, Atlanta, GA; American Century, Citibank, Phillip Morris and Sprint. She has been recognized in ArtForum, the New Art Examiner and Art Papers, among other publications.